000 03502Cam#a22004695i#4500
001 INGC-EBK-000603
003 AR-LpUFI
005 20220927110000.0
007 cr nn 008mamaa
008 130717s2014 gw | s |||| 0|eng d
020 _a9783642285547
024 7 _a10.1007/978-3-642-28554-7
_2doi
050 4 _aQ342
072 7 _aUYQ
_2bicssc
072 7 _aCOM004000
_2bisacsh
245 1 0 _aComputational Methods to Study the Structure and Dynamics of Biomolecules and Biomolecular Processes
_h[libro electrónico] : ;
_bFrom Bioinformatics to Molecular Quantum Mechanics /
_cedited by Adam Liwo.
260 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _axiv, 810 p. :
_bil.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Series in Bio-/Neuroinformatics,
_x2193-9349 ;
_v1
505 0 _aMolecular simulations: methodology -- Molecular simulations: applications -- Use of structural database or experimental information in modeling protein structure and dynamics -- Applications of molecular quantum mechanics.
520 _aSince the second half of the 20th century machine computations have played a critical role in science and engineering. Computer-based techniques have become especially important in molecular biology, since they often represent the only viable way to gain insights into the behavior of a biological system as a whole. The complexity of biological systems, which usually needs to be analyzed on different time- and size-scales and with different levels of accuracy, requires the application of different approaches, ranging from comparative analysis of sequences and structural databases, to the analysis of networks of interdependence between cell components and processes, through coarse-grained modeling to atomically detailed simulations, and finally to molecular quantum mechanics. This book provides a comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes. The twenty-two chapters, written by scientists from all over the world, address the theory and practice of computer simulation techniques in the study of biological phenomena. The chapters are grouped into four thematic sections dealing with the following topics: the methodology of molecular simulations; applications of molecular simulations; bioinformatics methods and use of experimental information in molecular simulations; and selected applications of molecular quantum mechanics. The book includes an introductory chapter written by Harold A. Scheraga, one of the true pioneers in simulation studies of biomacromolecules.
650 0 _aChemistry, Physical and theoretical.
_9298941
650 0 _aBioinformatics.
_9260231
650 0 _aProteins.
_9261528
650 1 4 _aEngineering.
_9259622
650 2 4 _aComputational Intelligence.
_9259845
650 2 4 _aComputational Biology/Bioinformatics.
_9260484
650 2 4 _aProtein Science.
_9261529
650 2 4 _aTheoretical and Computational Chemistry.
_9261124
650 2 4 _aMechanics.
_9260044
700 1 _aLiwo, Adam,
_eed.
_9261530
776 0 8 _iPrinted edition:
_z9783642285530
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-28554-7
912 _aZDB-2-ENG
929 _aCOM
942 _cEBK
999 _aSKV
_c28031
_d28031